D. Bleakman: search on Z-Library

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1

A role for AMPA receptors in mood disorders

Andrew Alt, Eric S. Nisenbaum, David Bleakman, Jeffrey M. Witkin

Journal:

Biochemical Pharmacology

Year:

2006

Language:

english

File:

PDF, 531 KB

english, 2006

2

Patients’ Perspectives on the Impact of Genital Psoriasis: A Qualitative Study

Cather, Jennifer Clay, Ryan, Caitriona, Meeuwis, Kim, Potts Bleakman, Alison J., Naegeli, April N., Edson-Heredia, Emily, Poon, Jiat Ling, Jones, Cate, Wallace, Ashley N., Guenther, Lyn, Fretzin, Scot

Journal:

Dermatology and Therapy

Year:

2017

Language:

english

File:

PDF, 614 KB

english, 2017

3

ChemInform Abstract: Synthesis of Willardiine and 6-Azawillardiine Analogues: Pharmacological Characterization on Cloned Homomeric Human AMPA and Kainate Receptor Subtypes.

D. E. JANE, K. HOO, R. KAMBOJ, M. DEVERILL, D. BLEAKMAN, A. MANDELZYS

Journal:

Year:

1998

File:

PDF, 33 KB

1998

4

Measurement of calcium flux through ionotropic glutamate receptors using Cytostar-T scintillating microplates

Adrian Cushing, Molly J Price-Jones, Robert Graves, Alison J Harris, Kelvin T Hughes, David Bleakman, David Lodge

Journal:

Journal of Neuroscience Methods

Year:

1999

Language:

english

File:

PDF, 99 KB

english, 1999

5

4-Alkylidenyl glutamic acids, potent and selective GluR5 agonists

S.Richard Baker, David Bleakman, Jesus Ezquerra, Barbara A Ballyk, Michele Deverill, Ken Ho, Rajender K Kamboj, Ivan Collado, Carmen Domı́nguez, Ana Escribano, Ana I Mateo, Concepcion Pedregal, Almude

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2000

Language:

english

File:

PDF, 148 KB

english, 2000

6

Irreversible Inhibition of High-Affinity [3H]Kainate Binding by a Novel Photoactivatable Analogue: (2′S,3′S,4′R)-2′-Carboxy-4′-(2-Diazo-1-Oxo-3,3,3-Trifluoropropyl)-3′-Pyrrolidinyl Acetate

Colin L. Willis, Dean A. Wacker, Richard D. Bartlett, David Bleakman, David Lodge, A. Richard Chamberlin, Richard J. Bridges

Journal:

Journal of Neurochemistry

Year:

1997

Language:

english

File:

PDF, 851 KB

english, 1997

7

Identification of Kainate Receptor-Mediated Intracellular Calcium Increases in Cultured Rat Cerebellar Granule Cells

Jonathan R. Savidge, David Bleakman, David R. Bristow

Journal:

Journal of Neurochemistry

Year:

1997

Language:

english

File:

PDF, 436 KB

english, 1997

8

Kainate receptor pharmacology and physiology

Journal:

Cellular and Molecular Life Sciences

Year:

1999

Language:

english

File:

PDF, 85 KB

english, 1999

9

In vitro and in vivo studies in rats with LY293558 suggest AMPA/kainate receptor blockade as a novel potential mechanism for the therapeutic treatment of anxiety disorders

Andrew Alt, Brianne Weiss, Ann Marie Ogden, Xia Li, Scott D. Gleason, David O. Calligaro, David Bleakman, Jeffrey M. Witkin

Journal:

Psychopharmacology

Year:

2006

Language:

english

File:

PDF, 221 KB

english, 2006

10

LY293558, a novel AMPA/GluR5 antagonist, is efficacious and well-tolerated in acute migraine

CN Sang, NM Ramadan, RG Wallihan, AS Chappell, FG Freitag, TR Smith, SD Silberstein, KW Johnson, LA Phebus, D Bleakman, PL Ornstein, B Arnold, SJ Tepper, F Vandenhende

Journal:

Year:

2004

Language:

english

File:

PDF, 93 KB

english, 2004

11

Tachykinins Potentiate N-Methyl-D-Aspartate Responses in Acutely Isolated Neurons from the Dorsal Horn

K. I. Rusin, D. Bleakman, P. S. Chard, M. Randic, R. J. Miller

Journal:

Journal of Neurochemistry

Year:

1993

Language:

english

File:

PDF, 930 KB

english, 1993

12

The AMPA Receptor Potentiator, LY404187 Modulates Expression of Neurotrophins: in vitro and in vivo Studies in Cortical and Hippocampal Brain Regions

M. J. O'Neill, M. Mackowiak, V. Lakics, C. A. Hicks, D. Bleakman, P. Skolnick

Journal:

CNS Drug Reviews

Year:

2004

Language:

english

File:

PDF, 48 KB

english, 2004

13

Mechanism of presynaptic inhibition by neuropeptide Y at sympathetic nerve terminals

Toth, Peter T., Bindokas, Vytautas P., Bleakman, David, Colmers, William F., Miller, Richard J.

Journal:

Year:

1993

File:

PDF, 784 KB

1993

14

10.1038/39315

Bleakman, David, Clarke, Vernon R. J., Ballyk, Barbara A., Hoo, Ken H., Mandelzys, Allan, Pellizzari, Andrew, Bath, Catherine P., Thomas, Justyn, Sharpe, Erica F., Davies, Ceri H., Ornstein, Paul L.,

Journal:

Year:

1997

Language:

english

File:

PDF, 455 KB

english, 1997

15

Antagonists of GLUK5-containing kainate receptors prevent pilocarpine-induced limbic seizures

Smolders, Ilse, Bortolotto, Zuner A., Clarke, Vernon R. J., Warre, Ruth, Khan, Ghous M., O'Neill, Michael J., Ornstein, Paul L., Bleakman, David, Ogden, AnnMarie, Weiss, Brianne, Stables, James P., Ho

Journal:

Nature Neuroscience

Year:

2002

Language:

english

File:

PDF, 369 KB

english, 2002

16

Structure−Activity Relationship Studies on N3-Substituted Willardiine Derivatives Acting as AMPA or Kainate Receptor Antagonists

Dolman, Nigel P., More, Julia C. A., Alt, Andrew, Knauss, Jody L., Troop, Helen M., Bleakman, David, Collingridge, Graham L., Jane, David E.

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 201 KB

english, 2006

17

Prevention of guanine nucleotide-induced reductions in muscarinic agonist binding to rabbit ileal submucosal membranes by lidamidine and tetracaine

David Bleakman, Richard J. Naftalin

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

1988

Language:

english

File:

PDF, 739 KB

english, 1988

18

Pharmacological characterization of a GluR6 kainate receptor in cultured hippocampal neurons

David Bleakman, Ann-Marie Ogden, Paul L Ornstein, Ken Hoo

Journal:

European Journal of Pharmacology

Year:

1999

Language:

english

File:

PDF, 180 KB

english, 1999

19

Sequential processing reactions in the formation of hormone amides

Alexandra BLEAKMAN, Derek G. SMYTH

Journal:

Year:

1987

Language:

english

File:

PDF, 493 KB

english, 1987

20

Synthesis and Pharmacological Characterization of N3-Substituted Willardiine Derivatives: Role of the Substituent at the 5-Position of the Uracil Ring in the Development of Highly Potent and Selective GLUK5 Kainate Receptor Antagonists

Dolman, Nigel P., More, Julia C. A., Alt, Andrew, Knauss, Jody L., Pentikäinen, Olli T., Glasser, Carla R., Bleakman, David, Mayer, Mark L., Collingridge, Graham L., Jane, David E.

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 504 KB

english, 2007

21

Calcium homeostasis in rat septal neurons in tissue culture

David Bleakman, John D. Roback, Bruce H. Wainer, Richard J. Miller, Neil L. Harrison

Journal:

Year:

1993

Language:

english

File:

PDF, 1.09 MB

english, 1993

22

The effects of ifenprodil and eliprodil on voltage-dependent Ca2+ channels and in gerbil global cerebral ischaemia

Catherine P. Bath, Louise N. Farrell, Jeremy Gilmore, Mark A. Ward, Caroline A. Hicks, Michael J. O'Neill, David Bleakman

Journal:

European Journal of Pharmacology

Year:

1996

Language:

english

File:

PDF, 882 KB

english, 1996

23

ω-conotoxin MVIIC reversibly inhibits a human N-type calcium channel and calcium influx into chick synaptosomes

C.J. Grantham, D. Bowman, C.P. Bath, D.C. Bell, D. Bleakman

Journal:

Neuropharmacology

Year:

1994

Language:

english

File:

PDF, 451 KB

english, 1994

24

Characteristics of a human N-type calcium channel expressed in HEK293 cells

D. Bleakman, D. Bowman, C.P. Bath, P.F. Brust, E.C. Johnson, C.R. Deal, R.J. Miller, S.B. Ellis, M.M. Harpold, M. Hans, C.J. Grantham

Journal:

Neuropharmacology

Year:

1995

Language:

english

File:

PDF, 1.16 MB

english, 1995

25

The effects of four general anesthetics on intracellular [Ca2+] in cultured rat hippocampal neurons

D. Bleakman, M.V. Jones, N.L. Harrison

Journal:

Neuropharmacology

Year:

1995

Language:

english

File:

PDF, 1.03 MB

english, 1995

26

In vitro and in vivo antagonism of AMPA receptor activation by (3s,4ar,6r,8ar)-6-[2-(1(2)h-tetrazole-5-yl)ethyl]decahydroisoquinoline-3-carboxylic acid

D.D. Schoepp, D. Lodge, D. Bleakman, J.D. Leander, J.P. Tizzano, R.A. Wright, A.J. Palmer, C.R. Salhoff, P.L. Ornstein

Journal:

Neuropharmacology

Year:

1995

Language:

english

File:

PDF, 1.10 MB

english, 1995

27

Pharmacological characterization of glutamatergic agonists and antagonists at recombinant human homomeric and heteromeric kainate receptors in vitro

A. Alt, B. Weiss, A.M. Ogden, J.L. Knauss, J. Oler, K. Ho, T.H. Large, D. Bleakman

Journal:

Neuropharmacology

Year:

2004

Language:

english

File:

PDF, 389 KB

english, 2004

28

Characterisation of UBP296: a novel, potent and selective kainate receptor antagonist

Julia C.A. More, Robert Nistico, Nigel P. Dolman, Vernon R.J. Clarke, Andrew J. Alt, Ann M. Ogden, Floris P. Buelens, Helen M. Troop, Eve E. Kelland, Fabio Pilato, David Bleakman, Zuner A. Bortolotto,

Journal:

Neuropharmacology

Year:

2004

Language:

english

File:

PDF, 512 KB

english, 2004

29

Anxiolytic-like effects through a GLUK5 kainate receptor mechanism

Andrew Alt, Brianne Weiss, Paul L. Ornstein, Scott D. Gleason, David Bleakman, Robert E. Stratford Jr., Jeffrey M. Witkin

Journal:

Neuropharmacology

Year:

2007

Language:

english

File:

PDF, 187 KB

english, 2007

30

ACET is a highly potent and specific kainate receptor antagonist: Characterisation and effects on hippocampal mossy fibre function

Sheila L. Dargan, Vernon R.J. Clarke, Gregory M. Alushin, John L. Sherwood, Robert Nisticò, Zuner A. Bortolotto, Ann M. Ogden, David Bleakman, Andrew J. Doherty, David Lodge, Mark L. Mayer, Stephen M.

Journal:

Neuropharmacology

Year:

2009

Language:

english

File:

PDF, 766 KB

english, 2009

31

Glutamate receptors and pain

David Bleakman, Andrew Alt, Eric S. Nisenbaum

Journal:

Seminars in Cell & Developmental Biology

Year:

2006

Language:

english

File:

PDF, 196 KB

english, 2006

32

Pharmacological effects of AMPA receptor potentiators LY392098 and LY404187 on rat neuronal AMPA receptors in vitro

M Gates, A Ogden, D Bleakman

Journal:

Neuropharmacology

Year:

2001

Language:

english

File:

PDF, 150 KB

english, 2001

33

Novel AMPA receptor potentiators LY392098 and LY404187: effects on recombinant human AMPA receptors in vitro

P Miu, K.R Jarvie, V Radhakrishnan, M.R Gates, A Ogden, P.L Ornstein, H Zarrinmayeh, K Ho, D Peters, J Grabell, A Gupta, D.M Zimmerman, D Bleakman

Journal:

Neuropharmacology

Year:

2001

Language:

english

File:

PDF, 174 KB

english, 2001

34

An AMPA receptor potentiator modulates hippocampal expression of BDNF: an in vivo study

Marzena Mackowiak, Michael J O’Neill, Caroline A Hicks, David Bleakman, Phil Skolnick

Journal:

Neuropharmacology

Year:

2002

Language:

english

File:

PDF, 419 KB

english, 2002

35

LY354740 is a Potent and Highly Selective Group II Metabotropic Glutamate Receptor Agonist in Cells Expressing Human Glutamate Receptors

D.D SCHOEPP, B.G JOHNSON, R.A WRIGHT, C.R SALHOFF, N.G MAYNE, S WU, S.L COCKERHAM, J PAUL BURNETT, R BELEGAJE, D BLEAKMAN, J.A MONN

Journal:

Neuropharmacology

Year:

1997

Language:

english

File:

PDF, 2.07 MB

english, 1997

36

Identification of Pore-forming Subunit of P-type Calcium Channels: an Antisense Study on Rat Cerebellar Purkinje Cells in Culture

S.E GILLARD, S.G VOLSEN, W SMITH, R.E BEATTIE, D BLEAKMAN, D LODGE

Journal:

Neuropharmacology

Year:

1997

Language:

english

File:

PDF, 644 KB

english, 1997

37

Activity of 2,3-benzodiazepines at Native Rat and Recombinant Human Glutamate Receptors In Vitro: Stereospecificity and Selectivity Profiles

DAVID BLEAKMAN, BARBARA A BALLYK, DARRYLE D SCHOEPP, ANDREW J PALMER, CATHERINE P BATH, ERICA F SHARPE, MARIE L WOOLLEY, HYWEL R BUFTON, RAJENDER K KAMBOJ, ISTVAN TARNAWA, DAVID LODGE

Journal:

Neuropharmacology

Year:

1996

Language:

english

File:

PDF, 1.16 MB

english, 1996

38

Electrophysiological characterisation of the human N-type Ca2+ channel II: Activation and inactivation by physiological patterns of activity

N.C.L McNaughton, D Bleakman, A.D Randall

Journal:

Neuropharmacology

Year:

1998

Language:

english

File:

PDF, 321 KB

english, 1998

39

The synaptic activation of the GluR5 subtype of kainate receptor in area CA3 of the rat hippocampus

M. Vignes, D. Bleakman, D. Lodge, G.L. Collingridge

Journal:

Neuropharmacology

Year:

1997

Language:

english

File:

PDF, 502 KB

english, 1997

40

Electrophysiological characterisation of the human N-type Ca2+ channel III: pH-dependent inhibition by a synthetic macrocyclic polyamine

N.C.L. McNaughton, C. White, B. Clark, C. Bath, D. Bleakman, A.D. Randall

Journal:

Neuropharmacology

Year:

1999

Language:

english

File:

PDF, 338 KB

english, 1999

41

LY339434, a GluR5 kainate receptor agonist

B Small, J Thomas, M Kemp, K Hoo, B Ballyk, M Deverill, A.M Ogden, A Rubio, C Pedregal, D Bleakman

Journal:

Neuropharmacology

Year:

1998

Language:

english

File:

PDF, 122 KB

english, 1998

42

Decahydroisoquinolines: novel competitive AMPA/kainate antagonists with neuroprotective effects in global cerebral ischaemia

Michael J O'Neill, Ann Bond, Paul L Ornstein, Mark A Ward, Caroline A Hicks, Ken Hoo, David Bleakman, David Lodge

Journal:

Neuropharmacology

Year:

1998

Language:

english

File:

PDF, 253 KB

english, 1998

43

The GluR5 subtype of kainate receptor regulates excitatory synaptic transmission in areas CA1 and CA3 of the rat hippocampus

M Vignes, V.R.J Clarke, M.J Parry, D Bleakman, D Lodge, P.L Ornstein, G.L Collingridge

Journal:

Neuropharmacology

Year:

1998

Language:

english

File:

PDF, 358 KB

english, 1998

44

Neuropharmacology of AMPA and kainate receptors

David Bleakman, David Lodge

Journal:

Neuropharmacology

Year:

1998

Language:

english

File:

PDF, 207 KB

english, 1998

45

[3H]ATPA: a high affinity ligand for GluR5 kainate receptors

Ken Hoo, Beatta Legutko, Geihan Rizkalla, Michele Deverill, C.R Hawes, Gareth J Ellis, Tine B Stensbol, Povl Krogsgaard-Larsen, Phil Skolnick, David Bleakman

Journal:

Neuropharmacology

Year:

1999

Language:

english

File:

PDF, 143 KB

english, 1999

46

Inhibitory Actions of Synthesised Polyamine Spider Toxins and Their Analogues on Neuronal Voltage-Activated Calcium Currents

Kathy G Sutton, Simon R Stapleton, Graham Timms, Jeremy Gilmore, Paul F Brust, David Bleakman, Roderick H Scott

Journal:

Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology

Year:

1997

Language:

english

File:

PDF, 161 KB

english, 1997

47

A Critical Role of a Facilitatory Presynaptic Kainate Receptor in Mossy Fiber LTP

Sari E Lauri, Zuner A Bortolotto, David Bleakman, Paul L Ornstein, David Lodge, John T.R Isaac, Graham L Collingridge

Journal:

Year:

2001

Language:

english

File:

PDF, 448 KB

english, 2001

48

A Role for Ca2+ Stores in Kainate Receptor-Dependent Synaptic Facilitation and LTP at Mossy Fiber Synapses in the Hippocampus

Sari E Lauri, Zuner A Bortolotto, Robert Nistico, David Bleakman, Paul L Ornstein, David Lodge, John T.R Isaac, Graham L Collingridge

Journal:

Year:

2003

Language:

english

File:

PDF, 577 KB

english, 2003

49

The effect of capsaicin on voltage-gated calcium currents and calcium signals in cultured dorsal root ganglion cells

D. Bleakman, J.R. Brorson, R.J. Miller

Journal:

British Journal of Pharmacology

Year:

1990

Language:

english

File:

PDF, 2.13 MB

english, 1990

50

Neuropeptide Y inhibits Ca2+ influx into cultured dorsal root ganglion neurones of the rat via a Y2 receptor

D. Bleakman, W.F. Colmers, A. Fournier, R.J. Miller

Journal:

British Journal of Pharmacology

Year:

1991

Language:

english

File:

PDF, 1.35 MB

english, 1991

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